The Talmadge area saw two serious car wrecks late Wednesday, one in which a pedestrian was killed.

In the fatal incident, around 8:30 p.m., the pedestrian, 59, was struck by a 29-year-old driver in a Honda sedan as he crossed El Cajon Boulevard at Altadena Drive, police said. The man died at the scene.

Alcohol did not appear to be a factor in the crash, according to Officer David Stafford. The victim has yet to be identified.

Locally, officials have been alarmed by the rise in deaths of pedestrians.

San Diego and Los Angeles were among the 10 U.S. cities with the highest number of pedestrians killed in traffic accidents in 2012, federal transportation officials have said.

In addition, according to the National Highway Traffic Safety Administration. 32 percent of the deaths happen from 8 p.m. to midnight, as in this case.

Federal officials have compiled a list of advice on how pedestrians can keep themselves safe and practices communities can put in place to protect them.

About three hours later Wednesday, in another incident, a woman, 22, was driving a 2003 Subaru west on the transition from Montezuma Road to northbound Fairmount Avenue when she lost control for unknown reasons, Stafford said. Her car careened off the ramp, struck a pole, then rolled over.

The woman was taken to a hospital to be treated for a broken arm and abrasions.

City News Service contributed to this report.