Illumina building
A building on the Illumina i3 campus in University City. Reuters/Mike Blake

In the wake of Carl Icahn’s proxy battle, Illumina has begun cutting jobs and announced plans Monday to exit part of its campus in University City.

The San Diego-based maker of genetic sequencing equipment said in a regulatory filing that it is committed to reducing its annual expenses by more than $100 million in 2023.

The reduction in workforce commenced on June 21 and will result in charges of $25 to $35 million, the company said.

The company did not say how may employees would be laid off, but media reports suggested it could be as high as 10%.

The real estate that Illumina plans to exit is the three-building i3 campus located on the north side of La Jolla Village Drive at Interstate 805. The company’s other headquarters buildings are located about half a mile south.

After a proxy battle with Icahn that came to a head at the annual shareholders meeting in May, long-time CEO Francis deSouza stepped down and the company announced a search for his successor.

Illumina’s core global workforce comprised about 10,200 full-time employees as of Jan. 1, according to a regulatory filing.

Reuters contributed to this article.

Chris Jennewein is founder and senior editor of Times of San Diego.