Business and political leaders from San Diego and Tijuana took their message of cross-border collaboration to Mexico City on Monday amid continued uncertainty around the U.S.-Mexico relationship.

“This trip and our mission as champions for cross-border commerce are more important than ever,” said Jerry Sanders, president and CEO of the San Diego Regional Chamber of Commerce, which organized the mission.

“Our region is a national model for successful cross-border commerce and it is critical that we bring the voice of our region’s business community to leaders in Mexico City to facilitate collaboration and to keep moving forward with the projects and policies necessary for economic growth,” he added.

America’s 8th largest city and Mexico’s 6th largest are increasingly pitching the combined Cali-Baja region as a location for investment and tourism. But President Trump’s criticism of the North American Free Trade Agreement and vow to build a massive wall along the border worries both cities.

The annual, four-day advocacy mission includes over 80 business, community and government leaders from both sides of the border who are meeting with top Mexican government officials and agencies to advocate for policies and initiatives important to regional growth and global competitiveness.

Among the leaders taking part are San Diego Mayor Kevin Faulconer, Tijuana Mayor Juan Manuel Gastélum and Mexican Consul General Marcela Celorio.

“The Tijuana-San Diego region is an economic development engine on a global scale, which is why the brotherhood between the two cities is closer and more solid today, than ever before. Despite efforts to build walls to divide us, we build bridges of understanding and cooperation,” said Gastélum.

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