*|DATE:F j, Y|*


Good morning, San Diego.

GLP-1s have baked themselves into the cultural lexicon over the past couple of years. You may have first heard about them from a celebrity’s off-handed mention of Ozempic, those medical commercials with an awfully-catchy jingle or one of the drug’s many mentions during this year’s Super Bowl.

The medication, originally conceived to treat Type 2 diabetes, has broken into the mainstream for its ability to aid weight loss by suppressing one’s appetite.

Putting the peptide’s popularity aside, we’re left with the reality that it’s a drug, and there are still question marks around its long-term side effects. The Salk Institute is working to answer those questions, and so far, researcher Sam Van de Velde is finding positive effects that extend beyond the realm of weight loss. His team’s findings have the potential to shake-up some perceptions of the drug.

San Diego Wave FC isn’t potentially shaking up anything – the club made a big splash Friday.

Catarina Macario, who has local roots as a Torrey Pines High alum and a product of the San Diego Surf youth soccer pipeline, had been widely reported to be interested in returning home. The Wave made her signing official Friday, announcing the forward’s addition to the club in what is widely believed to be a record-breaking deal.

Macario, who starred both overseas and as a member of the U.S. international squad, is not set to play this weekend, but will be introduced at Saturday’s match (snag a ticket fast). It looks like the Wave, once stacked with stars like Alex Morgan and Naomi Girma, has the right duo, in Macario and Ludmila, to launch a new era.

Jennifer Vigil, Afternoon Editor & Tessa Balc, Audience Engagement Producer


Today’s top story

Use of weight loss ‘wonder drugs’ has doubled. The Salk Institute is studying how far their benefits can go

By Thomas Murphy • Times of San Diego

GLP-1 drugs like Ozempic have become massively popular for their slimming side effects, but researchers continue to study their broader applications.


Times of San Diego thanks our corporate sponsors. Find out more about sponsorships and advertising opportunities here.


8 stories to start your day


Times of San Diego thanks our corporate sponsors. Find out more about sponsorships and advertising opportunities here.


Today’s opinion column

Opinion: When law enforcement targets ballots, it becomes voter suppression

A sheriff sworn to uphold the law has stepped into the election process, pursuing claims that do not withstand basic scrutiny.


Love this newsletter?
Show us with your donation.

Thank you for reading our morning update. Our nonprofit news team works hard to bring you essential news on local government, business, education, public safety and community affairs in San Diego County. But journalism is expensive, and we need your help. Thank you for your support.



Forwarded this email? Subscribe here to receive Morning Update.
Have a news tip? Email us at news@timesofsandiego.com.