Padres outfielder Hunter Renfroe complies as a fan asked him to sign the shirt she wore. Photo by Chris Stone

A pair of homers by Hunter Renfroe was not enough to rally a win for the San Diego Padres in the series opener game against the New York Mets at Petco Park on Monday night. The Friars lost 5-3.

The Pads were no match for Mets pitcher Jacob deGrom, who went for eight innings of two-run ball with eight strikeouts. The Friars were held scoreless for seven innings until Renfroe’s 431-foot homer deep in the left field that landed on the Western Metal Supply Company’s rooftop.

The homer was Renfroe’s longest in his career and the third-longest home run hit at Petco Park since 2015. After Jose Pirela scored off a double by Carlos Asuaje in the eighth inning, Renfroe led the Padres rally with a home run to start the ninth inning against closer Addison Reed.

Manuel Margot and Hector Sanchez each got a single off Reed when pinch-hitter Jabari Blash hit a fastball down the right-field line that looked to be a walk-off homer, but the ball curled to the right of the foul line.

“When I saw it go up, my initial thought was, ‘I got him,’” Blash said.

Reed got his 17th save after striking out Blash and a lineout by Matt Szczur.

“Doesn’t look like it was foul by much. A little gust and we win a baseball game,” Padres manager Andy Green said. “That’s a tough one.”

Also on Monday, the Padres traded a trio of pitchers to the Kansas City Royals. Trevor Cahill, Brandon Maurer and Ryan Buchter were traded for pitchers Matt Strahm and Travis Wood, infielder Esteury Ruiz and cash.

Up next is game two of the four-game series at 7:10 p.m. Tuesday at Petco Park.