Venable’s sixth homer of the season came just a pitch after the Padres challenged a call which resulted in a Clint Barmes double.
Barmes’ fly ball down the right field line was initially called foul, but after manager Pat Murphy challenged the call and Barmes was awarded second base.
Venable then came up and hit the game-winning shot.
“We’ve done enough talking, it’s time to start playing,” Venable said in a postgame interview with Fox Sports San Diego.
All but one of the Padres’ runs came via the home run.
Ross did enough on the mound to keep his team in the game, throwing six innings, striking out six and allowing three runs on four hits and five walks.
The other run for the Padres came on an RBI single from rookie catcher Austin Hedges in the fifth inning.