San Diego Padres right hander Andrew Cashner set a franchise record Wednesday afternoon  by striking out the first six batters to open the game against the Houston Astros.

However, the Friars were defeated Wednesday 7-2, and were swept by the Astros for the first time at Petco Park.

The Padres got one run off of Astros left hander Dallas Kuechel in the first inning thanks to an RBI double from right fielder Matt Kemp, but would not score again until the ninth inning.

Cashner finished the afternoon with 10 strikeouts through seven innings, while allowing three runs (two earned).

After starting the season 10-5, the Friars have dropped seven out of their last eight and finished the month of April with an 11-12 record.

“It’s a lot of games, but overall, you’ve seen us get off to a really good start [at] 10-5. And we’ve had a tough week,” Padres manager Bud Black said to Padres.com. “But I think we’ve seen some offense, we’ve seen some good pitching, we’ve seen some pitching that hasn’t been so good lately, especially out of the bullpen.”

The Padres have Thursday off, but will stay at home and open a three-game set against the Colorado Rockies starting Friday.

Right hander Ian Kennedy will get the start in the series opener against right hander Eddie Butler for the Rockies.

First pitch on Friday is scheduled for 7:10 p.m.

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