An FBI SWAT team raided an apartment in Otay Mesa early Wednesday morning, but few details about the operation were immediately disclosed.
A videographer at the scene reported that the SWAT team surrounded the apartment building in the 5600 block of Surfrider Way at 4:30 a.m. and called for occupants to surrender.
Agents were later seen escorting three people in handcuffs from a second-floor apartment.
Those arrested were transported to another location by San Diego Police officers.
The FBI declined to release any details about the operation, including the names of the detainees, saying it was part of an ongoing investigation.
OnScene.TV and City News Service contributed to this article.